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Current Publications

Author(s): Marie Lynn Miranda, PhD; Michele Casper, PhD; Joshua Tootoo, MCP; Linda Schieb, MSPH
Abstract - Techniques based on geographic information systems (GIS) have been widely adopted and applied in the fields of infectious disease and environmental epidemiology; their use in chronic disease programs is relatively new.
Author(s): Leonor Corsino, MD, MHS, Jennifer R. McDuffie, PhD, Jonathan Kotch, MD, MPH, Remy Coeytaux, MD, PhD, Bernard F. Fuemmeler, PhD, Gwen Murphy, PhD, MS, LDN, Marie Lynn Miranda, PhD, Brenda Poirier, MS, RB, PNP, BC, Janet Morton, RN, MS, David Reese, MBA, Sh
Abstract: BACKGROUND - Obesity is a prominent problem in the United States and in North Carolina. One way of combating it is with community-engaged interventions that foster collaboration between health-oriented organizations and community residents.
Author(s): Robert M. Califf, MD; Iain Sanderson, BM, BCh, MSc; Marie Lynn Miranda, PhD
Substantial age-adjusted reductions in cardiovascular mortality and morbidity over the past few decades are being challenged by increases in physical inactivity, diabetes mellitus, and obesity, creating a large and aging population with long-term cardiovascular disease (CVD). However, the US...
Author(s): Gretchen L Kroeger, Lynne Messer, Sharon E Edwards and Marie L Miranda
Abstract: Background - A growing corpus of research focuses on assessing the quality of the local built environment and also examining the relationship between the built environment and health outcomes and indicators in communities. However, there is a lack of research presenting a highly resolved...
Author(s): Sayanti Bhattacharya, Ashley A Dunham, Melissa A Cornish, Victoria A Christian, Geoffrey S Ginsburg, Jessica D Tenenbaum, Meredith L Nahm, Marie Lynn Miranda, Robert M Califf, Rowena J Dolor, and L Kristin Newby
Abstract - Current understanding of chronic diseases is based on crude clinical characterization, imaging studies, and laboratory testing that has evolved over decades. The Measurement to Understand Reclassification of Disease of Cabarrus/Kannapolis (MURDOCK) Study is a multi-tiered, longitudinal...
Author(s): Messer, L., Maxson, P., and Miranda, M.L
Abstract - The determinants that underlie a healthy or unhealthy pregnancy are complex and not well understood. We assess the relationship between the built environment and maternal psychosocial status using directly observed residential neighborhood characteristics (housing damage, property...
Author(s): M.L. Miranda, S.E. Edwards, R. Anthopolos, D. H. Dolinsky, A. R. Kemper
Abstract - The relationship between childhood obesity and aspects of the built environment characterizing neighborhood social context is understudied. This study evaluates the association between 7 built environment domains and childhood obesity in Durham, North Carolina. Measures of housing damage...
Author(s): Chang H.H., Reich B.J., and Miranda M.L
Summary - The paper describes a Bayesian spatial discrete time survival model to estimate the effect of air pollution on the risk of preterm birth. The standard approach treats prematurity as a binary outcome and cannot effectively examine time varying exposures during pregnancy. Time varying...
Author(s): Miranda, M.L., Edwards, S.E., Chang, H.H., and Auten, R.L
Abstract - Adverse birth outcomes are associated with exposure to air pollution during pregnancy. Road proximity is a simple, widely available metric for capturing local variation in exposure to traffic-related air pollution. We characterized maternal exposure to traffic-related air pollution...
Author(s): Buttke, D., Wolkin, A, Stapleton, H.M., and Miranda, M.L
Abstract - Polybrominated diphenyl ethers (PBDE) are flame retardants that were previously used in upholstery, fabrics, and household appliances. PBDEs have been linked to adverse health outcomes, including neurotoxicity, thyroid hormone dysregulation, endocrine disruption, and poor semen quality....
Author(s): G.K. Swamy, M.E. Garrett, M.L. Miranda, and A.E. Ashley-Koch
Abstract - Racial disparity in pregnancy outcomes is one of the most striking and poorly understood inequalities in American health. Genetic variability may be an important host factor influencing disparate birth outcomes between non-Hispanic black (NHB) and non-Hispanic white (NHW) women. Race-...
Author(s): Miranda, M.L., Messer, L., Kroeger, G
Abstract: Background - The built environment, a key component of environmental health, may be an important contributor to health disparities, particularly for reproductive health outcomes.
Author(s): L. C. Vinikoor-Imler, S.C. Gray, S.E. Edwards, M.L. Miranda
Summary - Gestational hypertension, pre-eclampsia and eclampsia are conditions that affect the health of both mothers and infants during and after pregnancy. Recent research indicates the importance of considering environmental, social and individual contributors to poor pregnancy outcomes. Our...
Author(s): Maxson, P., Edwards, S., Ingram, A., Miranda, M.L.
Abstract - Despite the well-established adverse birth and childhood health outcomes associated with maternal smoking, smoking rates among pregnant women remain high. Psychosocial health attributes, including anxiety, depression, perceived stress, self-efficacy, and personality characteristics, have...
Author(s): Anthopolos, R., Keating, M., Camann, D., and Miranda, M.L
Abstract - The objective of this study was to characterize the occurrence and concentration of pesticides and polycyclic aromatic hydrocarbons (PAH) in household dust in North Carolina. Human exposure to these contaminants in the indoor environment is of concern since little degradation takes place...
Author(s): D. Hastings and M.L. Miranda
Community-based operations research (CBOR) is the use of analytical methods with government and organizations in the formal and informal non-profit sector to improve the lives of individuals and communities. The beneficiaries of these methods tend to be localized, as well as members of...
Author(s): Chang H.H., Reich B.J., and Miranda M.L
Abstract - Exposures to air pollution during pregnancy have been suggested as risk factors for preterm birth; however epidemiological evidence remains mixed and limited. This paper examines the association between ambient levels of particulate matter
Author(s): R. Anthopolos, S.A. James, A.E. Gelfand, and M.L. Miranda
Abstract - Research on racial residential segregation (RRS) and birth outcomes has focused on RRS at a broad geographic scale, in an aspatial framework, and in northern US cities. We developed a spatial measure of neighborhood level racial isolation of blacks. We examined the association between...
Author(s): Miranda, M.L., Edwards, S.E., Myers, E.R.
Abstract: OBJECTIVES - Previous studies indicate that nulliparous women (i.e., women having no previous births) are at higher risk for adverse birth outcomes than multiparous women (i.e., women having had at least one previous birth). We examined whether part of the difference in adverse outcome...
Author(s): Anthopolos, R., James, S.A., Gelfand, A.E., Miranda, M.L
Abstract - Research on racial residential segregation (RRS) and birth outcomes has focused on RRS at a broad geographic scale, in an aspatial framework, and in northern US cities. We developed a spatial measure of neighborhood level racial isolation of blacks. We examined the association between...

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