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Current Publications

Author(s): S.E. Edwards, B. Strauss, and M.L. Miranda.
Abstract - Using geographic information systems to link administrative databases with demographic, social, and environmental data allows researchers to use spatial approaches to explore relationships between exposures and health. Traditionally, spatial analysis in public health has focused on the...
Author(s): B.W. Strauss, E.M. Valentiner, S. Bhattacharya, M.M. Smerek, A.A. Dunham, L.K. Newby, and M.L. Miranda
Abstract - This paper highlights methods for using geospatial analysis to assess, enhance, and improve recruitment efforts to ensure representativeness in study populations. We apply these methods to the Measurement to Understand Reclassification of Disease of Cabarrus/Kannapolis (MURDOCK) study, a...
Author(s): S.E. Edwards, P. Maxson, M.L. Miranda, and R.C. Fry.
Abstract - The objectives of this study were to examine cadmium (Cd) levels and relationships to demographics in an observational, prospective pregnancy cohort study in Durham County, North Carolina. Multivariable models were used to compare blood Cd levels across demographic characteristics.
Author(s): B. Neelon, A. Gelfand, and M.L. Miranda
Summary - Motivated by a study exploring geographic disparities in test scores among fourth graders in North Carolina, we develop a multivariate mixture model for the spatial analysis of correlated continuous outcomes. The responses are modelled as a finite mixture of multivariate normal...
Author(s): Randall A. Kramer, Leonard E. G. Mboera, Kesheni Senkoro, Adriane Lesser, Elizabeth H. Shayo, Christopher J. Paul and Marie Lynn Miranda
Abstract - The optimization of malaria control strategies is complicated by constraints posed by local health systems, infrastructure, limited resources, and the complex interactions between infection, disease, and treatment. The purpose of this paper is to describe the protocol of a randomized...
Author(s): Leonard E. G. Mboera, Randall A. Kramer, Marie Lynn Miranda, Stella P. Kilima, Elizabeth H. Shayo, Adriane Lesser
Abstract - The use of microbial larvicides, a form of larval source management, is a less commonly used malaria control intervention that nonetheless has significant potential as a component of an integrated vector management strategy. We evaluated community acceptability of larviciding in a rural...
Author(s): Anthopolos, Rebecca; Kaufman, Jay S.; Messer, Lynne C.; Miranda, Marie Lynna
Abstract - Background: Racial residential segregation has been associated with preterm birth. Few studies have examined mediating pathways, in part because, with binary outcomes, indirect effects estimated from multiplicative models generally lack causal interpretation. We develop a method to...
Author(s): B. Neelon, R. Anthopolos, and M.L. Miranda
Abstract - Motivated by a study examining geographic variation in birth outcomes, we develop a spatial bivariate probit model for the joint analysis of preterm birth and low birth weight. The model uses a hierarchical structure to incorporate individual and areal-level information, as well as...
Author(s): B. Neelon, H.H. Chang, Q. Ling, and S.N. Hastings
Abstract - Motivated by a study exploring spatiotemporal trends in emergency department use, we develop a class of two-part hurdle models for the analysis of zero-inflated areal count data. The models consist of two components—one for the probability of any emergency department use and one for the...
Author(s): Marie Lynn Miranda; Rebecca Anthopolos; Simon G. Gregory

In Reply - We recently published a study demonstrating an association between labor induction/augmentation and later diagnosis of autism.1 Letter writers expressed concern about overinterpretation of study findings that may inappropriately influence delivery room practice.


Author(s): Simone C Gray, Sharon E Edwards, Bradley D Schultz, and Marie Lynn Miranda
Abstract: Background - Both air pollution exposure and socioeconomic status (SES) are important indicators of children’s health. Using highly resolved modeled predictive surfaces, we examine the joint effects of air pollution exposure and measures of SES in a population level analysis of pregnancy...
Author(s): M.L. Miranda, R. Anthopolos, S.G. Gregory
To the Editors - Vintzileos and Ananth recently expressed concerns about overinterpretation of findings from our recent study that may inappropriately influence delivery room practice and the potential role of misclassification bias concerning the indicator for autism diagnosis used in our study.
Author(s): Veronica J. Berrocal, Marie Lynn Miranda, Alan E. Gelfand, Sourabh Bhattacharya
Abstract - A common data analysis setting consists of a collection of datasets of varying sizes that are all relevant to a particular scientific question, but which include different subsets of the relevant variables, presumably with some overlap.
Author(s): Alison P Sanders, Lisa Smeester, Daniel Rojas, Tristan DeBussycher, Michael C Wu, Fred A Wright, Yi-Hui Zhou, Jessica E Laine, Julia E Rager, Geeta K Swamy, Allison Ashley-Koch, Marie Lynn Miranda, Rebecca C Fry
Abstract - Cadmium (Cd) is prevalent in the environment yet understudied as a developmental toxicant. Cd partially crosses the placental barrier from mother to fetus and is linked to detrimental effects in newborns. Here we examine the relationship between levels of Cd during pregnancy and 5-...
Author(s): R. Anthopolos, J.S. Kaufman, L.C. Messer, M.L. Miranda
Abstract - Background. While racial residential segregation has been associated with preterm birth, few studies have examined mediating pathways, in part because with binary outcomes, indirect effects estimated from multiplicative models generally lack causal interpretation. We develop a method to...
Author(s): Simone C. Graya, Sharon E. Edwardsa, Marie Lynn Miranda
Abstract - Background: Although studies suggest that exposure to pollutants is associated with race/ethnicity and socio-economic status (SES), many studies are limited to the geographic regions where monitoring stations are located.
Author(s): Rachel L Richesson, Shelley A Rusincovitch, Douglas Wixted, Bryan C Batch, Mark N Feinglos, Marie Lynn Miranda, W Ed Hammond, Robert M Califf, Susan E Spratt
Abstract - Objective: This study compares the yield and characteristics of diabetes cohorts identified using heterogeneous phenotype definitions.
Author(s): Marie Lynn Miranda, Jeffrey Ferranti, Benjamin Strauss, Brian Neelon and Robert M. Califf
Abstract - Despite the rapid growth of electronic health data, most data systems do not connect individual patient records to data sets from outside the health care delivery system. These isolated data systems cannot support efforts to recognize or address how the physical and environmental context...
Author(s): Rebecca Anthopolos, Sharon E. Edwards, Marie Lynn Miranda
Abstract - Background: Research has documented the adverse relationship of child cognitive development with maternal prenatal smoking and poor birth outcomes. The potential, however, for maternal prenatal smoking to modify the association between birth outcomes and cognitive development is unclear.
Author(s): S.G. Gregory, R. Anthopolos, C. Osgood, C.A. Grotegut, and M.L. Miranda
Abstract - Importance: One in 88 children in the United States is diagnosed as having autism spectrum disorder. Significant interest centers on understanding the environmental factors that may contribute to autism risk.

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