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Current Publications

Author(s): Joshua R. Holmes, Joshua L. Tootoo, E. Julia Chosy, Amber Y. Bowie, Ranjani R. Starr

Background - Evidence shows that a person’s ZIP Code can affect his or her health. Health disparities are often geographically concentrated. For example, areas that lack sidewalks and safe places to exercise have lower levels of physical activity and higher rates of obesity than areas that have...

Author(s): Shepherd H. Schurman, Mercedes A. Bravo, Cynthia L. Innes, W. Braxton Jackson II, John A. McGrath, Marie Lynn Miranda, and Stavros Garantziotis

Abstract - Asthma is a common chronic lung disease, the incidence and severity of which may be influenced by gene-environment interactions. Our objective was to examine associations between single nucleotide polymorphisms (SNPs) and combinations of SNPs in the toll-like receptor 4 (TLR4) pathway...

Author(s): Mercedes A Bravo, Rebecca Anthopolos, Rachel T Kimbro, Marie Lynn Miranda

Abstract - Neighborhood characteristics such as racial segregation may be associated with type 2 diabetes mellitus, but studies have not examined these relationships using spatial models appropriate for geographically patterned health outcomes.

Author(s): Brian C Gulack, Rachel Greenberg, Reese H Clarkd, Marie Lynn Miranda, Martin L Blakely, Henry E Rice, Obinna O Adibe, Elisabeth T Tracy, P Brian Smith

Purpose - Inguinal hernias are common in premature infants, but there is substantial variation with regards to timing of repair. We sought to quantify and explain this variation.

Author(s): Matthew A. Davis, Rebecca Anthopolos, Joshua Tootoo, Marita Titler, Julie P. W. Bynum, Scott A. Shipman

Introduction - Non-physician clinicians now constitute nearly one-quarter of the US primary care workforce, and as such are expected to play a significant role in offsetting projected physician shortfalls.

Author(s): Cavin K. Ward-Caviness , William E. Kraus , Colette Blach , Carol S. Haynes , Elaine Dowdy , Marie Lynn Miranda , Robert Devlin , David Diaz-Sanchez , Wayne E. Cascio , Shaibal Mukerjee , Casson Stallings , Luther A. Smith , Simon G. Gregory , Svati H. Sh
Objective - Exposure to mobile source emissions is nearly ubiquitous in developed nations and is associated with multiple adverse health outcomes. There is an ongoing need to understand the specificity of traffic exposure associations with vascular outcomes, particularly in individuals with...
Author(s): Joshua D. Stein; Kapil G. Kapoor; Joshua L. Tootoo; Ruiyang Li; Alan Wagner; Chris Andrews; Marie Lynn Miranda

Abstract: Importance - As the United States considers how to best structure its health care services, specialty care availability is receiving increased focus. This study assesses whether patients lack reasonable access to ophthalmologists in states where optometrists have been granted expanded...

Author(s): Chad A.Grotegut, Emily Ngan, Melanie E.Garrett, Marie Lynn Miranda, Allison E.Ashley-Koch, Geeta K.Swamy

Background - Oxytocin is a potent uterotonic agent that is widely used for induction and augmentation of labor. Oxytocin has a narrow therapeutic index and the optimal dosing for any individual woman varies widely.

Author(s): Ryan A. Simmons, Leonard Mboera, Marie Lynn Miranda, Alison Morris, Gillian Stresman, Elizabeth L. Turner, Randall Kramer, Chris Drakeley and Wendy P. O’Meara

Abstract: Background- Measurements of anti-malarial antibodies are increasingly used as a proxy of transmission intensity. Most serological surveys are based on the use of cross-sectional data that, when age-stratified, approximates historical patterns of transmission within a population....

Author(s): S.E.Spratt, K.Pereira, B.B.Granger, B.C.Batch, M.Phelan, M.Pencina, M.L.Miranda, E.Boulware, J.E.Lucas, C.L.Nelson, B.Neely, B.A.Goldstein, P.Barth, R.L.Richesson, I.L.Riley, L.Corsino, E.R.M.Hinz, S.Rusincovitch, J.Green, A.B.Barton, et al.

Abstract - Objective: We assessed the sensitivity and specificity of 8 electronic health record (EHR)-based phenotypes for diabetes mellitus against gold-standard American Diabetes Association (ADA) diagnostic criteria via chart review by clinical experts. Materials and Methods: We...

Author(s): Cavin K. Ward-Caviness, Lucas M. Neas, Colette Blach, Carol S. Haynes, Karen LaRocque-Abramson, Elizabeth Grass, Z. Elaine Dowdy, Robert B. Devlin, David Diaz-Sanchez, Wayne E. Cascio, Marie Lynn Miranda, Simon G. Gregory, Svati H. Shah, William E. Kraus

Abstract - Air pollution is a worldwide contributor to cardiovascular disease mortality and morbidity. Traffic-related air pollution is a widespread environmental exposure and is associated with multiple cardiovascular outcomes such as coronary atherosclerosis, peripheral arterial disease, and...

Author(s): Mercedes A. Bravo, Rebecca Anthopolos, Michelle L. Bell, Marie Lynn Miranda
Abstract: Background - Researchers and policymakers are increasingly focused on combined exposures to social and environmental stressors, especially given how often these stressors tend to co-locate. Such exposures are equally relevant in urban and rural areas and may accrue disproportionately to...
Author(s): Joshua R. Ehrlich, Rebecca Anthopolos, Joshua Tootoo, Chris A. Andrews, Marie Lynn Miranda, Paul P. Lee, David C. Musch, Joshua D. Stein
Abstract: Purpose - To determine how strabismus diagnosis varies within a given community and across communities among children with Medicaid health insurance. Design Retrospective cohort analysis.
Author(s): Julie Strominger, Rebecca Anthopolos and Marie Lynn Miranda

Abstract: Background - Research surrounding the built environment (BE) and health has resulted in inconsistent findings. Experts have identified the need to examine methodological choices, such as development and testing of BE indices at varying spatial scales. 

Author(s): Pamela J. Maxson, Sharon E. Edwards, Ellis M. Valentiner, Marie Lynn Miranda
Abstract - Objectives Domains of psychosocial health have been separately connected to pregnancy outcomes. This study explores the relationship between five domains of psychosocial health and their joint association with prenatal health and pregnancy outcomes.
Author(s): Cavin K. Ward-Caviness, Lucas M. Neas, Colette Blach, Carol S. Haynes, Karen LaRocque-Abramson, Elizabeth Grass, Elaine Dowdy, Robert B. Devlin, David Diaz-Sanchez, Wayne E. Cascio, Marie Lynn Miranda, Simon G. Gregory, Svati H. Shah, William E. Kraus, El
Abstract - There is a growing literature indicating that genetic variants modify many of the associations between environmental exposures and clinical outcomes, potentially by increasing susceptibility to these exposures. However, genome-scale investigations of these interactions have been rarely...
Author(s): Dohyeong Kim, Zachary Brown, Richard Anderson, Clifford Mutero, Marie Lynn Miranda, Jonathan Wiener, Randall Kramer

Abstract - Decision analysis tools and mathematical modeling are increasingly emphasized in malaria control programs worldwide to improve resource allocation and address ongoing challenges with sustainability. However, such tools require substantial scientific evidence, which is costly to...

Author(s): Craig M. Butt, Marie Lynn Miranda, Heather M. Stapleton
Abstract - Polybrominated diphenyl ethers (PBDEs) flame retardants (FRs) were phased-out in the mid-2000s (penta- and octaBDE) and 2013 (decaBDE); however, their hydroxylated metabolites (OH-BDEs) are still commonly detected in human serum. Today, novel FRs such as Firemaster® 550, a mixture that...
Author(s): Sharon Edwards, Pamela Maxson, Nicole Sandberg, Marie Lynn Miranda
Abstract - Children born with low birth weight, preterm, or with fetal growth restriction may suffer from significant short and long term morbidity and mortality, making adverse pregnancy outcomes a major public health concern with significant health, social, and economic consequences for families...
Author(s): Christopher Leonetti, Craig M. Butt, Kate Hoffman, Marie Lynn Miranda, Heather M. Stapleton
Abstract - Legacy environmental contaminants such as polybrominated diphenyl ethers (PBDEs) are widely detected in human tissues. However, few studies have measured PBDEs in placental tissues, and there are no reported measurements of 2,4,6-tribromophenol (2,4,6-TBP) in placental tissues.

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